We’ve all known the frustration of minor memory lapses or forgetfulness like what happens when we forget where we’ve put our glasses or misplaced something we need right away. That’s just a tiny sample of the frustration of the Alzheimer’s experience.

Alzheimer’s disease is brought on by the buildup of toxic proteins, called beta amyloid and tau, in the brain.

Beware of the 5 Leading Causes

  • Anti-Anxiety Medication – Benzos (benzodiazepines) like lorazepam (Ativan), alprazolam (Xanax) and clonazepam (Klonopin) taken for more than three months was associated with up to a 51% increase in Alzheimer’s disease, according to a study published in the British Medical Journal.
  • Trauma to the Head – Brain injuries can leave some people with chronic inflammation of the brain and when microglia are in a constant pro-inflammatory state, they’re not able to clear amyloid beta (which destroys neurons) from the brain effectively.
  • Sleep Deprivation – Sleep loss increases the amount of tau in the brain which alters learning, memory and communication between neurons. Since the body eliminates toxins such as amyloid beta protein and tau during sleep, a lack of sleep is a form of stress on the body.
  • Lonliness – Being alone is great therapy for some but, essentially, humans are social creatures. Interaction with others is not just desirable, it’s necessary for good health. There were links found between loneliness and the development of dementia in a study in the Journal of Neurology, Neurosurgery and Psychiatry. Researchers found that loneliness gives older adults 1.63 times the odds of developing dementia.
  • “Brain Diabetes” – Like other cells in the body, brain cells can develop insulin resistance. Neuroscientist, Suzanne de la Monte, MD, of Brown University believes that Alzheimer’s is a metabolic disease that affects the brain. (Brain cells use glucose as fuel and insulin tells these cells to take up glucose in the blood.)

“Any organ can be affected by insulin resistance,” de la Monte says. “You can have it in the liver- we call that non-alcoholic fatty liver disease. If you get it in the kidney, we call it renal disease. If you get it in the brain, we call it Alzheimer’s.”

Her research over the past few years has revealed that this creates a toxic environment for the brain, leading to the harmful buildup of proteins and neuron death seen in Alzheimer’s.  Preliminary studies have shown that inhaled insulin can help reduce symptoms of Alzheimer’s dementia.

How Picamilon Helps

Picamilon is a hybrid nootropic (a Smart Drug also known as N-nicotinoyl-GABA) which provides a tranquilized state of being without causing lethargy. It helps with anxiety and insomnia.

Picamilon is derived from two natural compounds: nicotinic acid (niacin) and gamma-aminobutyric acid (GABA).  It’s the neurotransmitter GABA bound to Vitamin B3.


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