WHY ADRAFINIL IS POPULAR (Adrafinil Vs Modafinil)

Because Adrafinil is a premium nootropic supplement and is sold as such, it’s accessible to anyone who shops online, to use at their discretion. This freedom of widespread distribution has sky-rocketed Adrafinil’s popularity primarily among students, techies and the office crowd. Pretty soon, we’ll see it in everyone’s medicine cabinet alongside the pain-killers and cough syrup. We’ll be comparing this drug to it’s competition (Adrafinil Vs Modafinil), so we will quickly understand the key differences between them.

That doesn’t downplay the fact that Adrafinil is a powerful cognitive enhancer that provides razor sharp focus to the user, along with energy and motivation.

ADRAFINIL VS MODAFINIL AND PROVIGIL

Both Adrafinil and Provigil are derivatives of Modafinil. Provigil is the branded version of Modafinil and Adrafinil is a prodrug of Modafinil. Chemically, the structure of Adrafinil is almost identical to Modafinil except for the addition of an OH (Hydroxyl group) to its amide nitrogen which forms a hydroxylamine.

Provigil —very similar to Nuvigil and Armodafinil— is manufactured by Cephalon and all have the same effects. They all provide Modafinil to the brain. Armodafinil (Nuvigil) is an enantiopure drug. It is the R-enantiomer of Modafinil (which is sold as Provigil). There is very little difference in their chemical structures.

So, how does Adrafinil vs Modafinil and Provigil? In essence, since Modafinil and Provigil are identical twins, Adrafinil is the only challenger. How is Adrafinil different from Modafinil and Provigil? —Very simply, it’s milder and acts a little slower. Adrafinil is gentler and to be experienced with similar strength to Modafinil, it should be taken in slightly larger doses.

Why choose Adrafinil vs Modafinil and Provigil (or Modafinil=Provigil)? One fairly good reason why people choose Adrafinil is because Provigil requires a doctor’s prescription in order to purchase it at a pharmacy, whereas Adrafinil does not. Adrafinil can be bought online without any legal hassles. And, it’s cheaper. It’s gentler, cheaper and more readily available than Modafinil and Provigil.

ARMODAFINIL VS MODAFINIL VS ADRAFINIL

Some people feel that Armodafinil is an improvement on Modafinil because it’s “cleaner” and lower dosages are required. Because Armodafinil is enantiopure Modafinil, it is possibly a purer version of Modafinil. The difference is subtle because Modafinil already contains 50% Armodafinil. Albeit, Armodafinil is more expensive.

The question is: Is Armodafinil an improvement on Modafinil? Armodafinil is a derivative of Modafinil and was apparently developed at the same time as Modafinil’s patent expired. Does that mean that it was tweaked and re-patented as Armodafinil?

When comparing Armodafinil vs Modafinil vs Adrafinil, what are the significant differences?  Are Adrafinil, Modafinil, Provigil and Armodafinil different names for the same animal? —In some ways, yes. Modafinil is the common denominator. Armodafinil and Adrafinil deliver Modafinil to the brain. This is the wake-promoting agent used in the treatment of narcolepsy, obstructive sleep apnea and sleep disorders, etc as sleep medications.

All these medications are being increasingly used by healthy individuals to enhance vigilance, concentration and focus to compete in work environments and school. Both Modafinil and Armodafinil have been used to treat ADHD, prescribed off-label.

ARMODAFINIL VS MODAFINIL VS ADRAFINIL: WHAT’S THE DIFFERENCE?

Chemical Breakdown: Modafinil contains 50% r-modafinil (armodafinil) and 50% s-modafinil. In other words, Modafinil contains 50% Armodafinil.

Duration: Because Armodafinil lasts a few hours longer than Modafinil, it can pose a problem for insomniacs and disrupt the normal sleeping schedule.

Effects: Both Modafinil and Armodafinil affect the brain in exactly the same way with identical results.

Quality: Armodafinil is a more pure and potent form of Modafinil requiring a slightly lower dosage (150 mg vs 200 mg) and is also more expensive. On the other hand, Adrafinil requires a higher dosage for the same results (300 mg).

Efficacy: Since there has so far been no real proof that Armodafinil is more effective than Modafinil, why spend more for the same results? For some who demands a purer form of Modafinil, it might be worth the added expense.

FDA APPROVAL: Modafinil was developed and used in clinical studies before Armodafinil was introduced. The FDA approved Modafinil in 1998 and Armodafinil in 2007.

CHEMICAL DIFFERENCES OF ARMODAFINIL VS MODAFINIL VS ADRAFINIL

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Strangely enough, Armodafinil is a mirror-image of Modafinil called an “enantiomer molecule”.  Nevertheless, there is an important chemical difference between them.  Modafinil contains R and S enantiomers of the Modafinil molecule.  This mixture of both R and S enantiomers is “racemic” because they are in equal proportions (50/50). Adrafinil is a prodrug of Modafinil and a percentage of it converts to Modafinil in the liver.

MODAFINIL VS ADRAFINIL REDDIT

So, what’s the chatter about Modafinil vs Adrafinil Reddit trending? A couple of years ago, someone mentioned using a 1 to 2 ratio for Adrafinil vs Modafinil dosage in order to get the same effects. (In other words, dosing 400 mg of Adrafinil to substitute for 200 mg of Modafinil.) Their report was that it worked for them.

Another Reddit follower noted that it’s rough on your kidneys to take Adrafinil every day. They felt that “Modafinil is better because it’s the end product. It kicks in quickly and works well. Adrafinil may work just as well for some but not for others.”

Someone else noted that Adrafinil is the precursor of Modafinil in that it came first and led to the discovery of Modafinil. The two have the same effects but Adrafinil takes longer to take effect. They said, “Adrafinil metabolizes into Modafinil but it has side effects which the cleaner and more pure Modafinil only has to a far lesser degree. And Adrafinil acts on the liver in that it builds up and can cause liver damage after prolonged use. However, Modafinil is much less likely to do so.”

(“Modafinil vs Adrafinil, Reddit” – Modafinil scores points because of the kidney and liver dialogue. —But, are these worries justified?)

ADRAFINIL VS MODAFINIL REDDIT

(The following article was submitted to Reddit.)

FIRST EXPERIENCE WITH ADRAFINIL

submitted 10 months ago by R. Michael Ballow

Backstory: “I’ve been experimenting with nootropics for 6 years. I’ve tried virtually everything. My favorite stacks are Mr Happy variants. I love Oxiracetam, like Aniracetam, and am also fond of Noopept at small doses.

I’ve been meaning to try the Afinil analogs for quite some time, but in the interest of doing it legally (I live in the US), I’ve waited. Might get a script from a doc for Moda. But I wanted to try Adrafinil nonetheless.

“Dose: 150MG

Modafinil Equivalent (according to the consensus): 50MG

Onset: 40 minutes.

Full onset: 1 hour.

Method: Capsuled the dose myself w/ capsule maker, 1 “00” capsule, and a milligram scale.

“So – all I can say so far is holy sh*t. In that first 40 minutes, I felt a wakefulness that I have never felt before. It’s like I got 20 hours of sleep in a temperature controlled room, in total darkness, with an angel breathing on my face. I was also extremely aware of everything, similar to the feeling I always have, having been trained as a combat soldier (and did a tour in Iraq) in the United States Army, but this was a lot more intense. An entirely new level of vigilance.

“THINGS GOT REALLY INTERESTING”

“At the 1 hour marker, things got really interesting.

“I normally take a stack of Uridine monophosphate, CDP Choline, Caffeine, and ALCAR to really crank up the knob on focus and intense brain function – but that normally leaves me stimulated.

“I feel similar wakefulness/focus elements with Adrafinil, but without the stimulatory effect, which is pretty cool. Really cool actually.

“I started to notice (while on the phone with a parts vendor for a company I own) a verbal fluency increase right around 1 hour in. I haven’t been this verbally fluent in quite some time. Close, but not this. This is some other thing.

ADEPT ~ COMPETENET ~ CONFIDENT

“I’ve begun some of my work for the day, which I do mostly on my laptop from wherever I’m at, at the time. And so far, I’ve had more of a singular focus on specific tasks than I have in quite some time. I just feel adept. Competent. And confident as a result.

“My wakefulness at 1-1.5 hours in is basically insane. I feel super rested. Super aware. Super energized, and super focused.

“Overall – this, so far, has been a great experience. I read about people having bad experiences with the afinil analogs, and I suspect that for some people, they’re taking entirely too much. This dose was perfect for me.

“I took it early in the morning, to prevent any sleep related issues later on. We’ll see if I played that card right. I won’t dose again on it today, for that very reason, and to be honest, I don’t need it.

“I didn’t drink coffee, take any other nootropics, or do anything otherwise performance optimizing (like meditating, for example), and I’m as dialed in as I can get.

“So – first experience with Adrafinil = nearly perfect. Will definitely happily insert this into my nootropics arsenal. This will be useful in a myriad of applications.”

In Adrafinil Vs Modafinil, Reddit, this article scores a myriad of points for Adrafinil.

ADRAFINIL VS MODAFINIL DEPRESSION

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When it comes to depression, Modafinil can be prescribed by your doctor which means we can buy Modafinil vs Adrafinil in stores rather than having to go online which is the only place where Adrafinil is available for purchase. But, having read the above review in “Adrafinil Vs Modafinil Reddit”, it seems that most of us would opt to try Adrafinil instead of the prescription drug. Yes, we should definitely discuss these decisions with our doctor if we are under a doctor’s care for depression. If your doctor agrees, why not try it?

Using Adrafinil vs Modafinil, depression is eliminated. How can one be depressed when there are so many interesting and educational opportunities around? When your mind is fully focused, your body is energized and you are motivated, depression is no longer a part of the picture.

DON’T LET DEPRESSION GET YOU DOWN

Got SAD? If Seasonal Affective Disorder is getting you down this winter, you’re not alone. Many of us who never suffer from depression at other times of the year are a little low after a few weeks of low vitamin D3 (emitted from the sun’s rays).  If you suffer the occasional bout of depression and are not under a doctor’s care for it, Adrafinil is an alternative to Modafinil. Here are some other reasons to choose the Adrafinil vs Modafinil, depression blaster:

Adrafinil does not require a prescription and it’s less expensive than Modafinil. Modafinil is linked to such unpleasant side effects of adrafinil such as headache, diarrhea, upset stomach, back pain and nausea. If dosed improperly, it may also worsen sleep disorders. Plus with Adrafinil Vs Modafinil dosage, the dosage of Modafinil is much stronger per milligram. Presumably, that makes Adrafinil a little safer milligram for milligram as potential sleep medications.

ADRAFINIL VS MODAFINIL

Any arguments pitting Adrafinil vs. Modafinil may seem silly considering that Adrafinil is a prodrug of Modafinil. Either of these two popular nootropics or Eugeroics will put Modafinil in your system. However, because a prescription is required for Modafinil, and it is scheduled under U.S. law, those looking to get hold of it for nootropic purposes will probably be looking for an alternative. Adrafinil easily qualifies as the best substitute.

The upside of Adrafinil is that it can be purchased legally without a prescription. That makes Adrafinil accessible to students or those who don’t really require medication for health reasons. Whereas, technically, it’s illegal to possess Modafinil in the US without a prescription and if you buy it online, essentially, you are breaking the law. –Granted, prosecutions are rare.

The question is, “Which is better Modafinil vs. Adrafinil?” And, does Adrafinil work as well as Modafinil?

Modafinl has enjoyed popularity with students as a smart drug, as well as for graveyard shift workers who depend on its ability to help them function well throughout their shift.  Consider it one of the best wakefulness-promoting agents available to provide a quick boost of mental energy without the expenditure of the usual side effects experience from taking amphetamines like Adderall. (Some of these side effects include edginess, hypertension, perspiring, headaches and tachycardia.)

It may be easy to assume that because Modafinil is a prescription drug, it is therefore preferable to Adrafinil. The truth is that studies have varying conclusions with the Modafinil vs. Adrafinil comparison test.

WHAT IS ADRAFINIL?

Adrafinil was created in the French Laboratoires Lafon in the late 1970’s by the same biochemists who developed Modafinil. In the mid 80’s, in France as an experimental treatment for narcolepsy, sold under the brand name, Olmifon.

Researchers soon discovered that Adrafinil was unique in that it did not make the user hyper-active in the way that other stimulants, amphetamines and xanthenes acted in the body. Instead, Adrafinil fights sleepiness with additional mental energy to enable one to focus, concentrate and function normally as one would after a good night’s sleep.

Due to its psychostimulatory activity, Adrafinil has begun to be an off-label primarily by those who want help staying awake or need to sharpen their focus. People were using it as a cognitive enhancer and study aid.  Some even claim that their creative ability has been improving along with their ability to retain and retrieve memory more effectively. Adrafinil’s ability to affect the glutamate receptors in the brain probably have something to do with that.

Another claim was that Adrafinil’s anti-depressant and Anxiolytic effects help to relieve depression.

Although the exact way that Adrafinil and Modafinil act in the body has yet to be define, researchers suspect that these nootropics promote wakefulness via histaminergic signaling.

SOME OF ADRAFINIL’S BENEFITS:

  • Promotes Wakefulness
  • Stimulates Mental Energy
  • Improves Attention Span
  • Sharpens Focus
  • Improves Mood
  • Has a Calming Influence
  • Non-Prescription
  • Cheaper than Modafinil

SIDE EFFECTS:

  • Increases Liver Enzymes – This may pose health risks long term.
  • May Cause Skin Conditions
  • Can Cause Upset Stomach
  • May Cause Overstimulation

MODAFINIL VS ADRAFINIL FOR SALE

Many who purchase Modafinil overseas bring it into the country without incident. That’s not to say that a large catch of Modafinil would go unattested if found among minors. On the other hand, Adrafinil (which is almost identical in nature to Modafinil) is an innocuous dietary supplement, readily available at a lower cost than Modafinil. That’s not to say you can buy Modafinil vs Adrafinil in stores. Modafinil can only be purchased in the US as a prescription drug, while Adrafinil is not yet available in stores.

WONDER BOOST

For many people, the fact that Adrafinil is unregulated in the US you can purchase cheaper as a dietary supplement makes it more accessible and safer to use. In essence, Adrafinil’s popularity is due in large part to its accessibility as a supplement. —But, what a supplement. Wonder Bread’s got nothing on this wonder boost.

Another point scored for Adrafinil vs Modafinil is that Adrafinil is not harsh or severe in its approach. For many people, this is a good thing, meaning Adrafinil’s benefits come on smoothly and naturally.

THE NATURAL APPROACH

To those who ask, “Which is better –Modafinil vs Adrafinil?” the answer is probably a matter of choice. It’s a matter of how you best enjoy the experience of being on nootropics.

Adrafinil almost makes you feel as though the enhancements are natural and your own body operates and elevates your level of awareness that feels quite natural and controllable. It doesn’t give you the jitters like a cup of coffee. Do not underestimate it’s magic. The stamina and focus derived from using it are deeply empowering.

Adrafinil gives you a clear mind, thoughts are well-arranged and productivity is off the charts vs Modafinil dosage. Yet, there’s no edgy, tenseness involved at all. It just seems that the body is working at full capacity. And that’s a good thing.

MODAFINIL VS ADRAFINIL

Adrafinil is exactly like Modafinil with the addition of an OH (hydroxyl group) to the amide nitrogen, forming a hydroxylamine.

For some people, Adrafinil is not as robust as Modafinil. This may be the major scoring feature for Modafinil vs Adrafinil.

Less potent? Perhaps you could say the difference between which is better, Modafinil vs Adrafinil is like the difference between smoothly transitioning from gear to gear into high gear and staying in high gear all day without any swerves or jerks. —While Modafinil makes you “feel” the rush. Some of us prefer to feel it to ensure we’re getting value from our purchase. Others like to feel more in control. In the end, a lot depends on the opinion of the user and their personal preferences when it comes to which is better: Modafinil vs Adrafinil.

Converting a fraction of adrafinil is to Modafinil, while the rest is metabolizes to inactive modafinilic acid. It’s not very clear how much Adrafinil actually converts to Modafinil. It takes more Adrafinil to achieve the same results as an equal dose of Modafinil. In other words, less Modafinil does the same job.

More About Modafinil

Some prefer Modafinil because they see it as a more direct approach. They feel that Adrafinil is a less efficient method of incorporating Modafinil into the body’s system. —Another point for Modafinil vs Adrafinil.

The approval of Modafinil in the United States was in 1998, not long after the release of Adrafinil. This is founded in Laboratoires Lafon in France. Modafinil’s performance as a wakefulness enhancing agent attracted the attention of the US military and law enforcement agencies so that it became a standard supplement for military personnel, especially U.S. Air force pilots on long missions.

Modafinil and Adrafinil share similarities, but the effects of Modafinil are deemed faster- acting and longer-lasting. The U.S. FDA has approved it as a prescription drug limited to the treatment of narcolepsy, obstructive sleep apnea, and shift work sleep disorder. This aspect of Modafinil means those with prescriptions may buy Modafinil vs Adrafinil in stores.

A variety of neurological conditions and psychological disorders such as Parkinson’s disease, ADHD, depression, etc. have been a use of off-label.

Some believe that it gives athletes unfair advantage in competition, both nootropics are going to be on the list of ban substances list by the World Anti-Doping Agency (WADA).

SOME BENEFITS OF MODAFINIL:

  • Do not usePromotes Wakefulness
  • Provides a Boost to Mental Energy
  • Lessens Mental Fatigue
  • Sharpens Focus
  • Relieves Anxiety
  • The Liver does not Metabolize Modafinil
  • Better for Long Term
  • Requires Smaller Dose
  • Lifts Mood
  • Faster-Acting and Longer-Lasting

SIDE EFFECTS:

  • Renders Birth Control Ineffective
  • May Cause Hyperactivity
  • This should not be Used with Other Stimulants
  • Do not use Modafinil if you have Cardiac Conditions
  • Do not used with Yohimbine

 

MODAFINIL VS ADRAFINIL FOR SALE

It’s easy to buy Modafinil online but to purchase it at a store requires a doctor’s prescription. Many prefer this regulated approach and feel more secure with a doctor’s recommendation behind them. Since Adrafinil is not available in stores, Modafinil vs Adrafinil for sale gains a point.

THE LIVER RUMORS

For those who are concerned about the health of their liver, there has been some mention that the conversion of Adrafinil to Modafinil in the liver, which involves the participation of liver enzymes, may cause stress on this organ.

It is unclear what CYP450 isoform (liver enzyme) is going into action to bring about the conversion and there is no convincing evidence that Adrafinil causes any harm to the liver. It’s more likely that alcohol (even in small amounts) is considerably more harmful to the liver. Hepatotoxicity caused by alcohol is being unmistakably proven.

Apparently, the rumor going around that Adrafinil causes liver damage all began when a user reported elevated transaminases in their blood test. (Transaminases are liver enzymes.) However, there are many reasons for transaminases to elevate and this isolated incident doesn’t really prove anything worth worrying about.

ADRAFINIL VS MODAFINIL DOSAGE

The standard dosage of modafinil is 200 mg. Some who are sensitive to drugs may halve the dose. A recent study showed that 2 doses of 200 mg was more effective in treating narcolepsy than a single dose of 200 mg in the morning. That makes the range of dosage for Modafinil 100 – 400 mg per day.

Typically, the dosage for Adrafinil is 300 mg though some take this twice in the day. A dose of 600-1200 mg of Modafinil is necessary to achieve similar effects as using Adrafinil which is because only part of Adrafinil is converting to Modafinil.

Since Adrafinil is a prodrug (precursor) that is converting to Modafinil in the body, it is effecting the use of it as to Modafinil that is nearly identical.

While the half-life of Adrafinil is about 5 hours, its effects last much longer due to the fact that Modafinil as the active metabolite has a 14-hour half-life.

Appearance: Adrafinil is a whitish powder with an orange tint, while Modafinil is white or off-white.

SOMETHING TO CONSIDER

Due to wide variables of sensitivities in the consumers, the effects of Adrafinil Vs Modafinil on the individual will vary. Studies suggest that both eugeroics affect the dopamine in the reward center of the brain. Although there is very little potential for recreational abuse in these drugs, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) encourages users to be cautious in their use of either.

Categories: Supplements

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