Are There Benefits to Using Centrophenoxine with Piracetam in a Nootropic Stack?

You just can’t find anything as popular as Piracetam, if you’re looking for a nootropic supplement to boost cognition. For this reason and others (which we’ll go into) Piracetam is great for beginners. Piracetam’s popularity continues to grow even though there are other supplements, like Aniracetam, Oxiracetam, Pramiracetam and Noopept which may be even more potent.

Greater Than the Sum of Their Parts

Furthermore, when two nootropics join forces, the results are greater than the sum of their two parts. So, those seeking a little more from their supplement should definitely consider “stacking”. For example, Piracetam’s benefits are tremendously increased when taken in tandem with Centrophenoxine. Taking Centrophenoxine with Piracetam makes a super team. Centrophenoxine is a cholinergic that packs an extra punch to any of the racetam family members. Let’s consider more of the benefits of building a stack with Centrophenoxine and Piracetam.

Why Centrophenoxine?

Centrophenoxine, which is an excellent source of choline, is a supplemental support and, when used in combination with other racetams, provides the extra choline necessary to fire on all cylinders.  Although it will deliver major cognitive benefits on its own, it’s greatly enhanced when stacked.  Centrophenoxine is well known for its ability to prevent mental decline that usually comes with old age.  The reason for this is because it delivers choline over the blood brain barrier to keep brain cells healthy.  This means that the deterioration of neurons and their synapses is prevented.

This has been proven when it was used on mice during a study to research and memory loss.  Centrophenoxine was not only able to slow down the aging process, but actually reversed it. This is another consideration of taking this smart drug. The effects continue on into old age.

How Does it Work?

Centrophenoxine increases the glucose delivered to your brain cells.  As a result, this increases the energy that the brain metabolizes.  Oxygen levels also increase which provides the necessary environment needed for concentration and alertness.  It’s good to know that these benefits which are fantastic short-term, are also long term, enduring neural enhancements.

Recommended Dosage

We recommend a dose of this nootropic of 500 mg, divided over the morning and afternoon. AntiAgingCentral’s Centrophenoxine capsules come in 250 mg dose.


Perhaps the greatest reason why Piracetam has become so popular is because it is safe.  While it delivers a powerful boost to the brain, it is also gentle, nontoxic and with few side effects.  Over time your focus, concentration, and memory improve.  These enhancements are lasting and enduring.  In fact, a positive side effect is that your mood will be improved.  This is due to an increase in blood flow and oxygen levels.  So, don’t be surprised if your energy levels also are off the charts.  Some have claimed that using Piracetam has made them smarter and better able to remember things.

By adding Piracetam to your supplements, you may get a lot more than what you thought you were going to get. It may be the solution for a lot more than just focus and memory. The bottom line is that, for some, this is the answer they’ve been looking for.

Piracetam Stimulates the Cholinergic System

How are all of these benefits made possible?  The key is found in the cholinergic system of your brain.  When it’s stimulated by a nootropic such as Piracetam, the result is cognitive enhancement.  Your cognitive ability depends on sending and receiving signals and this is driven by the acetylcholine neurotransmitter.  Acetylcholine develops neurons and synapses as well as the ability to store information and form connections.  Since Piracetam will increase the levels of the acetylcholine neurotransmitter, you can memorize, learn, and focus at a much higher level. However, that choline needs to be in supply and it doesn’t usually present in such high levels unless it’s supplemented. That’s your job. You’ll want to find a good source of choline.

The Best Time to Take Piracetam

Because Piracetam is water soluble, it’s best to take it before breakfast and/or lunch on an empty stomach. We suggest a daily dose of 800 mg, twice per day.

Using Centrophenoxine with Piracetam in Tandem

The reason why we stack nootropics is because each nootropic has its own strengths.  If you’re wondering why we suggest that you stack Centrophenoxine with Piracetam it’s because while Piracetam signals the brain to release more acetylcholine, it’s Centrophenoxine that provides it. Therefore, if the demand is increased, there must be a supply. While using Piracetam, if you’re a little short on choline, it may cause a headache when using Piracetam alone.

We’re Not Getting Enough Choline

About 90% of the population of the US is estimated to be deficient in choline. And, though there are many food sources for choline, most of us are not getting enough. As a result, using Piracetam can quickly deplete your supply and bring on a headache.

If You Use Nootropics, Make Sure to Get Enough Choline

To experience the full benefit of nootropic use, it’s important that you get sufficient choline. If you don’t get enough, it stands to reason that you won’t get the full effects of the nootropic you’re using. The solution is to stack a source of choline with the nootropic you choose to use. In order to raise the level of choline in your brain, you can take Alpha GPC, Citicoline, or Centrophenoxine along with nootropics such as Piracetam. You’ll find that building stacks can result in a better outcome without the negative reaction from an insufficient supply of choline.


While we do recommend using Centrophenoxine with Piracetambut everyone’s body chemistry is a little different just as our finger prints differ. It may take a little experimenting to discover your “sweet spot” —the exact dosage and combination that provides all the benefits you’ve been looking for.

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